Inverted Microscopes for Life Science Research

Advanced Live Cell Imaging – High Performance at a Practical Price

Inverted Microscope for Research Excellence

Compatible and User-Friendly

Achieve research excellence with the AVT100 Series, a line of compatible and user-friendly inverted biological microscopes.
    • High-performance imaging for advanced life science research at a fraction of the cost of premium brands
    • Clear, flexible, and user-friendly design for efficient lab workflows
  • Model options:
      • AVT110 – Manual configuration
      • AVT160 – Fully motorized system
  • Supports multiple observation modes: Brightfield, Phase contrast, Differential Interference Contrast (DIC),  Fluorescence
  • Ergonomic and integration-ready design for comfortable, long-term use
  • Advanced research compatibility, including confocal and super-resolution imaging

Optimized Software and Cross-Brand Compatibility for Lab Efficiency 

Hardware consistency, smarter software:

  • Minimal hardware differences across brands like AVT and others
  • Software is the true differentiator—our system is optimized for reliable, everyday lab use
  • Delivers consistent performance across diverse research applications

Optimized for Nikon objective lenses:

  • Fully compatible with Nikon series lenses for high-quality imaging
  • Easy lens replacement and upgrade options
  • Unlike Zeiss and Leica (limited to proprietary systems), Nikon compatibility ensures greater flexibility and accessibility

From Essential to Advanced: Inverted Microscopes for Life Sciences

  • AVT110 Manual: Versatile research inverted microscope with plan semi-apochromatic objectives for cover glass correction, supporting advanced techniques like confocal and super-resolution.
  • AVT120 Intelligent Manual: User-friendly, highly integrated inverted microscope featuring plan semi-apochromatic objectives and support for brightfield, phase contrast, DIC, fluorescence, and Hoffman phase contrast with multiple image ports.
  • AVT150 Motorized: Software-controlled motorized inverted microscope for rapid, precise operation, increasing efficiency and accuracy while reducing phototoxicity.
  • AVT160 Motorized: Fully electric inverted microscope with front operation screen and integrated handle for maximum ease of use and minimal workspace clutter.
AVT110/AVT120
AVT150
AVT160

Application

Ideal for a variety of biological research tasks, including:

  • Brightfield, phase contrast, and DIC observation
  • Label-free live cell imaging, including bacteria
  • Fixed tissue and thin section analysis
  • Small organism imaging
  • Adherent and reproductive cell studies
  • Routine cell culture monitoring

Operation & User Experience

  • Familiar Workflow: Designed with a user interface inspired by Nikon systems, offering an intuitive experience for users already familiar with mainstream setups.
  • Flexible Configuration: The system operates without requiring proprietary software, allowing users to integrate it with their preferred camera analysis tools. A standard interface ensures compatibility.
  • Advanced Features Available: For setups with a display or electronic control, functions closely resemble Nikon’s standard imaging software, offering enhanced automation and control.

Technical Resource

Brightfield

Modular design enables brightfield, phase contrast, and DIC imaging. The NIS infinite optical system with semi-apochromatic objectives corrects aberrations for bright, high-resolution images. Phase contrast offers clear visualization at high magnifications, while DIC provides glare-free, pseudo-3D imaging for thick samples—without the need for costly optics.

Brightfield
DIC
Phase Contrast

Fluorescnece 

Advanced coating technology enhances fluorescence imaging with higher transmittance, sharper cut-off, and improved detection efficiency. Ultra-high-performance filters and a six-position lighting pillar enable multi-color imaging. Reduced scattered light and autofluorescence ensure brighter, clearer images with a high signal-to-noise ratio for reliable, high-resolution fluorescence observation.

FITEpi-fluorescence filter cube
DAPI Epi-fluorescence filter cube
TRITC Epi-fluorescence filter cube
B/G Epi-fluorescence filter cube

Specifications

AVT110 AVT120 AVT 150 AVT 160
Optical system NIS Infinite Optical System
Eye piece SW10X/22 ·SW10X/25 ·EW12.5X/17.5 ·WF15X/16 ·WF20X/12
Viewing Head Seidentopf Trinocular Head(build-in bertrand lens),inclined at 45°, Interpupilary Distance 47-78mm
Objective N-iPLFN PH Plan S-APO Phase Contrast Objective 4X, 10X, 20 X, 40X, 60X  N-iPLFN Plan S-APO Objective 4X, 10X, 20 X, 40X, 60X  N-PLAPO PlanAPO Objective10X, 20 X, 40X, 60X, 100X
Nosepiece Sextuple Nosepiece with DIC Prism Slot Encoded Sextuple Nosepiece with DIC Prism Slot Electric Sextuple Nosepiece with DIC Prism Slot Electric Sextuple Nosepiece with DIC Prism Slot
Condenser Long Working Distance Turret Condenser, NA0.55, WD=26 mm, with 6 Modules for Phase Contrast, DIC and Brightfield Long work distance electric Turret condenser, NA 0.55, WD=26 mm, with 6 Modules for Phase Contrast, DIC and Brightfield Long work distance electric Turret condenser, NA0.55, WD=26 mm, with 7 Modules for PhaseContrast, DIC and Brightfield
Transmission Lighting Kohler illumination 12V 100W halogen lamp Kohler Illumination 5W LED Kohler Illumination 10W LED Kohler illumination 5W LED
Epi-illumination ·100W mercury lamp  · LED fluorescent lighting LED fluorescent lighting
Focusing System Coaxial Coarse and Fine Adjustment Electric coaxial coarse inching lifting mechanism
Stage 3 Layers Mechanical Stage, Moving Range 130x85mm, Flexible Knob, available for Different Size Small Stage. The moving range: 130×100mm, the maximum speed: 50mm/s, and the resolution: 0.1 μm.  Small worktables of different sizes can be installed on the top stage as required. The moving range: 115×75mm, the maximum speed: 71mm/s, and the resolution: 0.1 μm.  Small worktables of different sizes can be installed on the top stage as required.
Auxillary Stage Terasaki plate, φ38 mm,φ54 mm plate, General support plate, 96-hole plate tray
Intermediate magnification Multiplier 1X, 1.5X Multiplier 1X, 1.5X, CF Optics Multiplier 1X, 1.5X
Display Built In & Real-Time Display: Instant, at-a-glance view of all current microscope settings and real-time updates for manual adjustments. Dual synchronized displays for live imaging and microscope control via intuitive software; real-time updates from built-in display; perfectly synchronized settings for a clear overview.
Observation method Brightfield, Phase contrast, DIC, Fluorescence, Hoffman phase contrast
Filter Turntable Epi-fluorescent filter turntable Encoded Epifluorescent Turntable Electric Epi-fluorescent filter turntable
Fluorescent Illuminator Supports up to six epifluorescence filters for simultaneous imaging of specimens stained with multiple fluorophores. Delivers bright, high-contrast images with minimal scattered light and autofluorescence for a superior signal-to-noise, S/N, ratio.
Dimension 56x56x51 cm 62x57x47 cm 62x57x47 cm 62x57x47 cm
Weight 36 kg 36 kg 40 kg 40 kg

FAQ

  1. What types of imaging modes does this microscope support?
    Our microscope supports brightfield, phase contrast, and Differential Interference Contrast (DIC) imaging, enabling clear visualization of living cells, thin tissue sections, and transparent samples without staining.

     

  2. Can I use Zeiss or Leica objective lenses with this microscope?
    This system is optimized for Nikon objective lenses. Zeiss and Leica lenses are part of closed systems and are not compatible.

     

  3. Is the system suitable for live cell imaging?
    Yes, it’s ideal for label-free live cell observation, allowing real-time monitoring without fluorescent markers—perfect for long-term culture studies.

     

  4. Does the microscope require proprietary software?
    No. The system can be used with standard image analysis software via a common interface, offering flexibility for integration into existing workflows.

     

  5. Who typically uses this microscope?
    It’s widely used by universities, research institutes, biotech and pharmaceutical companies, and cosmetic R&D labs for a range of biological and medical applications.

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